Streptococcal Pyrogenic Exotoxin B (SPEB) (AA 146-398) antibody
SPEB
Reactivity: Streptococcus pyogenes
ELISA, WB
Host: Rabbit
Polyclonal
unconjugated
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- Target See all Streptococcal Pyrogenic Exotoxin B (SPEB) Antibodies
- Streptococcal Pyrogenic Exotoxin B (SPEB)
- Binding Specificity
- AA 146-398
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Reactivity
- Streptococcus pyogenes
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
- Application
- ELISA, Western Blotting (WB)
- Cross-Reactivity
- Streptococcus pyogenes
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: WB:1:500-1:5000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Streptococcal Pyrogenic Exotoxin B (SPEB)
- Alternative Name
- speB (SPEB Products)
- Synonyms
- streptococcal pyrogenic exotoxin B antibody, speB antibody
- Background
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Background: Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing (By similarity).
Aliases: speB antibody, M28_Spy1721 antibody, Streptopain antibody, EC 3.4.22.10 antibody, Exotoxin type B antibody, SPE B antibody, Streptococcal cysteine proteinase antibody, Streptococcus peptidase A antibody, SPP antibody
- UniProt
- Q48R29
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