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Streptococcal Pyrogenic Exotoxin B (SPEB) (AA 146-398) antibody

SPEB Reactivity: Streptococcus pyogenes ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7179505
  • Target See all Streptococcal Pyrogenic Exotoxin B (SPEB) Antibodies
    Streptococcal Pyrogenic Exotoxin B (SPEB)
    Binding Specificity
    AA 146-398
    Reactivity
    • 4
    • 3
    Streptococcus pyogenes
    Host
    • 7
    Rabbit
    Clonality
    • 7
    Polyclonal
    Conjugate
    • 2
    • 2
    • 2
    • 1
    Un-conjugated
    Application
    ELISA, Western Blotting (WB)
    Cross-Reactivity
    Streptococcus pyogenes
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Streptococcal Pyrogenic Exotoxin B (SPEB)
    Alternative Name
    speB (SPEB Products)
    Synonyms
    streptococcal pyrogenic exotoxin B antibody, speB antibody
    Background

    Background: Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing (By similarity).

    Aliases: speB antibody, M28_Spy1721 antibody, Streptopain antibody, EC 3.4.22.10 antibody, Exotoxin type B antibody, SPE B antibody, Streptococcal cysteine proteinase antibody, Streptococcus peptidase A antibody, SPP antibody

    UniProt
    Q48R29
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