Outer capsid glycoprotein VP7 antibody (AA 51-326) (Biotin)

Catalog No. ABIN7179172

Product Details anti-Outer capsid glycoprotein VP7 Antibody (Biotin)

Target: Outer capsid glycoprotein VP7 (ADRSJV19_S9GP1) (Outer Capsid Protein (ADRSJV19_S9GP1))

Binding Specificity: AA 51-326

Reactivity: Rotavirus A

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Outer capsid glycoprotein VP7 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Rotavirus A

Purification: >95%, Protein G purified

Immunogen: Recombinant Rotavirus A Outer capsid glycoprotein VP7 protein (51-326AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Outer capsid glycoprotein VP7

Target: Outer capsid glycoprotein VP7 (ADRSJV19_S9GP1) (Outer Capsid Protein (ADRSJV19_S9GP1))

Alternative Name: Outer capsid glycoprotein VP7 (ADRSJV19_S9GP1 Products)

Synonyms: Outer capsid glycoprotein VP7 antibody, LOC7011359 antibody

Target Type: Viral Protein

Background:

Background: Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. Following entry into the host cell, low intracellular or intravesicular Ca2+ concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion. This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.

Aliases: antibody, Outer capsid glycoprotein VP7 antibody

UniProt: P10501