DIO3 antibody (AA 37-278) (HRP)
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- Target See all DIO3 Antibodies
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
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Binding Specificity
- AA 37-278
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DIO3 antibody is conjugated to HRP
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Application
- ELISA
- Cross-Reactivity
- Rat
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Rat Thyroxine 5-deiodinase protein (37-278AA)
- Isotype
- IgG
- Top Product
- Discover our top product DIO3 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
- Alternative Name
- Dio3 (DIO3 Products)
- Synonyms
- 5DIII antibody, DIOIII antibody, txdi3 antibody, dioiii antibody, XL-15 antibody, itdi3 antibody, D3 antibody, TXDI3 antibody, iodothyronine deiodinase 3 antibody, deiodinase, iodothyronine, type 3 antibody, deiodinase, iodothyronine, type III antibody, deiodinase, iodothyronine type III antibody, deiodinase, iodothyronine, type 3 L homeolog antibody, DIO3 antibody, dio3 antibody, Dio3 antibody, dio3.L antibody
- Background
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Background: Responsible for the deiodination of T4 (3,5,3\\\',5\\\'-tetraiodothyronine) into RT3 (3,3\\\',5\\\'-triiodothyronine) and of T3 (3,5,3\\\'-triiodothyronine) into T2 (3,3\\\'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
Aliases: Dio3 antibody, Itdi3 antibody, Txdi3 antibody, Thyroxine 5-deiodinase antibody, EC 1.21.99.3 antibody, 5DIII antibody, DIOIII antibody, Type 3 DI antibody, Type III iodothyronine deiodinase antibody
- UniProt
- P49897
- Pathways
- Hormone Activity
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