SOCS3 antibody (AA 1-225)
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- Target See all SOCS3 Antibodies
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
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Binding Specificity
- AA 1-225
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SOCS3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Human, Rat
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Rat Suppressor of cytokine signaling 3 protein (1-225AA)
- Isotype
- IgG
- Top Product
- Discover our top product SOCS3 Primary Antibody
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anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibody
SOCS3 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) antibodySOCS3 Reactivity: Human ELISA, IF, IHC (p) Host: Mouse Monoclonal 1E4 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 155-225) antibodySOCS3 Reactivity: Mouse, Rat ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibodySOCS3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-224) antibodySOCS3 Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) antibodySOCS3 Reactivity: Human WB Host: Mouse Monoclonal SO1 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-226) antibodySOCS3 Reactivity: Human ELISA Host: Mouse Monoclonal 1E4 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibodySOCS3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 71-85), (Middle Region) antibodySOCS3 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) antibodySOCS3 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:500-1:2000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
- Alternative Name
- Socs3 (SOCS3 Products)
- Background
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Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis. Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells. Regulates IL-6 signaling in vivo. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize IL6ST (By similarity).
Aliases: Socs3 antibody, Cish3Suppressor of cytokine signaling 3 antibody, SOCS-3 antibody, Cytokine-inducible SH2 protein 3 antibody
- UniProt
- O88583
- Pathways
- JAK-STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
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