FCGR3A antibody (PE)

Catalog No. ABIN7178460

Product Details anti-FCGR3A Antibody (PE)

Target: FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCGR3A antibody is conjugated to PE

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: Affinity purified

Immunogen: Recombinant Protein

Isotype: IgG1, IgG1 kappa

Application Details

Application Notes: Recommended dilution:IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FCGR3A

Target: FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))

Alternative Name: FCGR3A (FCGR3A Products)

Synonyms: CD16 antibody, CD16A antibody, FCG3 antibody, FCGR3 antibody, FCGRIII antibody, FCR-10 antibody, FCRIII antibody, FCRIIIA antibody, IGFR3 antibody, Fcgr4 antibody, Fc fragment of IgG receptor IIIa antibody, FCGR3A antibody, Fcgr3a antibody

Background:

Background: COC16 reacts with human CD16, a 50-65 kDa Fcg receptor IIIa (FcgRIII), expressed on NK cells, monocytes/macrophages and granulocytes. It is a human NK cell associated antigen. CD16 is a low affinity receptor for IgG which functions in phagocytosis and ADCC, as well as in signal transduction and NK cell activation. The CD16 antibody blocks the binding of soluble immune complexes to granulocytes.This clone is cross reactive with non-human primate.1. Knapp, W.,et al. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.2. Stroncek, D.F., et al. (1991) Blood 77:1572.3. Wirthmueller, U., et al.  (1992) J. Exp. Med. 175:1381.4. Barclay, N.A., et al. (1993) The Leucocyte Antigen FactBook, CD16 section, Academic Press Inc.,San Diego, Calfornia, p. 136.

Aliases: N/A

UniProt: P08637