PDGFD antibody (AA 24-370)

Catalog No. ABIN7177754

Product Details anti-PDGFD Antibody

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Binding Specificity: AA 24-370

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Platelet-derived growth factor D protein (24-370AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PDGFD

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Alternative Name: Pdgfd (PDGFD Products)

Synonyms: IEGF antibody, SCDGF-B antibody, SCDGFB antibody, Scdgfb antibody, rSCDGF-B antibody, PDGFD antibody, 1110003I09Rik antibody, platelet derived growth factor D antibody, platelet-derived growth factor, D polypeptide antibody, PDGFD antibody, Pdgfd antibody

Background:

Background: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing (By similarity). Has oncogenic potential and can induce tumor formation. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.

Aliases: Pdgfd antibody, Scdgfb antibody, Platelet-derived growth factor D antibody, PDGF-D antibody, Spinal cord-derived growth factor B antibody, SCDGF-B) [Cleaved into: Platelet-derived growth factor D antibody, latent form antibody, PDGFD latent form), Platelet-derived growth factor D antibody, receptor-binding form antibody, PDGFD receptor-binding form)] antibody

UniProt: Q925I7

Pathways: RTK Signaling, Platelet-derived growth Factor Receptor Signaling