IRF8 antibody (AA 1-424)
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- Target See all IRF8 Antibodies
- IRF8 (Interferon Regulatory Factor 8 (IRF8))
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Binding Specificity
- AA 1-424
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRF8 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Human, Mouse
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Mouse Interferon regulatory factor 8 protein (1-424AA)
- Isotype
- IgG
- Top Product
- Discover our top product IRF8 Primary Antibody
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- Application Notes
- Recommended dilution: WB:1:500-1:5000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- IRF8 (Interferon Regulatory Factor 8 (IRF8))
- Alternative Name
- Irf8 (IRF8 Products)
- Synonyms
- zgc:92252 antibody, IRF8 antibody, MGC140338 antibody, DKFZp469B0320 antibody, H-ICSBP antibody, ICSBP antibody, ICSBP1 antibody, IRF-8 antibody, icsbp1 antibody, AI893568 antibody, Icsbp1 antibody, Myls antibody, interferon regulatory factor 8 antibody, interferon regulatory factor 8 L homeolog antibody, irf8 antibody, IRF8 antibody, irf8.L antibody, Irf8 antibody
- Background
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Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5\\\'-TGAnTCA/GAAA-3\\\'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.
Aliases: Irf8 antibody, Icsbp antibody, Icsbp1 antibody, Interferon regulatory factor 8 antibody, IRF-8 antibody, Interferon consensus sequence-binding protein antibody, ICSBP antibody
- UniProt
- P23611
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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