HSPA1B antibody (AA 2-642) (HRP)

Catalog No. ABIN7177280

Product Details anti-HSPA1B Antibody (HRP)

Target: HSPA1B (Heat Shock 70kDa Protein 1B (HSPA1B))

Binding Specificity: AA 2-642

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPA1B antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Heat shock 70 kDa protein 1B protein (2-642AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HSPA1B

Target: HSPA1B (Heat Shock 70kDa Protein 1B (HSPA1B))

Alternative Name: Hspa1b (HSPA1B Products)

Background:

Background: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation.

Aliases: Hspa1b antibody, Hcp70.1 antibody, Hsp70-1 antibody, Hsp70a1 antibody, Hspa1 antibody, Heat shock 70 kDa protein 1B antibody, Heat shock 70 kDa protein 1 antibody, HSP70.1 antibody

UniProt: P17879