FAIM3 antibody (AA 18-262) (Biotin)

Catalog No. ABIN7177186

Product Details anti-FAIM3 Antibody (Biotin)

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Binding Specificity: AA 18-262

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAIM3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FAIM3

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Alternative Name: Fcmr (FAIM3 Products)

Synonyms: FAIM3 antibody, FCMR antibody, TOSO antibody, 1810037B05Rik antibody, FcmuR antibody, Toso antibody, Fc fragment of IgM receptor antibody, FCMR antibody, Fcmr antibody

Background:

Background: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Aliases: Fcmr antibody, Faim3 antibody, TosoFas apoptotic inhibitory molecule 3 antibody, IgM Fc fragment receptor antibody, Regulator of Fas-induced apoptosis Toso antibody

UniProt: A1KXC4