YAF2 antibody (AA 1-204) (HRP)

Catalog No. ABIN7175957

Product Details anti-YAF2 Antibody (HRP)

Target: YAF2 (YY1 Associated Factor 2 (YAF2))

Binding Specificity: AA 1-204

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YAF2 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human YY1-associated factor 2 protein (1-204AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for YAF2

Target: YAF2 (YY1 Associated Factor 2 (YAF2))

Alternative Name: YAF2 (YAF2 Products)

Synonyms: MGC75686 antibody, YAF2 antibody, zgc:136577 antibody, si:ch211-155a11.5 antibody, 2810021M11Rik antibody, YY1 associated factor 2 antibody, YY1-associated factor 2 antibody, yaf2 antibody, YAF2 antibody, LOC100221270 antibody, Yaf2 antibody

Background:

Background: Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates \'Lys-9\' of histone H3, suggesting that it is involved in chromatin-remodeling.

Aliases: MGC41856 antibody, YAF2 antibody, YAF2_HUMAN antibody, YY1-associated factor 2 antibody

UniProt: Q8IY57