YAF2 antibody (AA 1-204)
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- Target See all YAF2 Antibodies
- YAF2 (YY1 Associated Factor 2 (YAF2))
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Binding Specificity
- AA 1-204
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This YAF2 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human YY1-associated factor 2 protein (1-204AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- YAF2 (YY1 Associated Factor 2 (YAF2))
- Alternative Name
- YAF2 (YAF2 Products)
- Synonyms
- MGC75686 antibody, YAF2 antibody, zgc:136577 antibody, si:ch211-155a11.5 antibody, 2810021M11Rik antibody, YY1 associated factor 2 antibody, YY1-associated factor 2 antibody, yaf2 antibody, YAF2 antibody, LOC100221270 antibody, Yaf2 antibody
- Background
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Background: Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates \'Lys-9\' of histone H3, suggesting that it is involved in chromatin-remodeling.
Aliases: MGC41856 antibody, YAF2 antibody, YAF2_HUMAN antibody, YY1-associated factor 2 antibody
- UniProt
- Q8IY57
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