YTHDF2 antibody (AA 201-500) (Biotin)

Catalog No. ABIN7175943

Product Details anti-YTHDF2 Antibody (Biotin)

Target: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Binding Specificity: AA 201-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YTHDF2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human YTH domain-containing family protein 2 protein (201-500AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for YTHDF2

Target: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Alternative Name: YTHDF2 (YTHDF2 Products)

Synonyms: MGC82537 antibody, HGRG8 antibody, NY-REN-2 antibody, YTH N(6)-methyladenosine RNA binding protein 2 L homeolog antibody, YTH N6-methyladenosine RNA binding protein 2 antibody, ythdf2.L antibody, YTHDF2 antibody

Background:

Background: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability (PubMed:24284625, PubMed:26046440). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:22575960, PubMed:24284625, PubMed:25412658, PubMed:25412661). Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation (PubMed:24284625, PubMed:26046440).

Aliases: 9430020E02Rik antibody, CAHL antibody, CLL associated antigen KW 14 antibody, CLL-associated antigen KW-14 antibody, HGRG8 antibody, High glucose regulated protein 8 antibody, High-glucose-regulated protein 8 antibody, NY REN 2 antibody, Renal carcinoma antigen NY REN 2 antibody, Renal carcinoma antigen NY-REN-2 antibody, YTH domain family 2 antibody, YTH domain family member 2 antibody, YTH domain family protein 2 antibody, YTH N6 methyladenosine RNA binding protein 2 antibody, YTHD2_HUMAN antibody, YTHDF 2 antibody, YTHDF2 antibody

UniProt: Q9Y5A9