SLC7A6 antibody (AA 473-515)
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- Target See all SLC7A6 Antibodies
- SLC7A6 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 6 (SLC7A6))
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Binding Specificity
- AA 473-515
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC7A6 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Y+L amino acid transporter 2 protein (473-515AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SLC7A6 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 6 (SLC7A6))
- Alternative Name
- SLC7A6 (SLC7A6 Products)
- Synonyms
- id:ibd2834 antibody, LAT-2 antibody, LAT3 antibody, y+LAT-2 antibody, AI643885 antibody, solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 antibody, solute carrier family 7 member 6 antibody, solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 L homeolog antibody, solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 antibody, slc7a6 antibody, Slc7a6 antibody, SLC7A6 antibody, slc7a6.L antibody
- Background
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Background: Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
Aliases: SLC7A6 antibody, KIAA0245 antibody, Y+L amino acid transporter 2 antibody, Cationic amino acid transporter antibody, y+ system antibody, Solute carrier family 7 member 6 antibody, y(+)L-type amino acid transporter 2 antibody, Y+LAT2 antibody, y+LAT-2 antibody
- UniProt
- Q92536
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