WWOX antibody (AA 1-180)

Catalog No. ABIN7175871

Product Details anti-WWOX Antibody

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Binding Specificity: AA 1-180

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WWOX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human WW domain-containing oxidoreductase protein (1-180AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for WWOX

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Alternative Name: WWOX (WWOX Products)

Background:

Background: Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.

Aliases: 5330426P09Rik antibody, 9030416C10Rik antibody, Aberrant WW domain-containing oxidoreductase antibody, D16S432E antibody, EC 1.1.1.- antibody, EIEE28 antibody, FOR antibody, FRA16D antibody, Fragile site FRA16D oxidoreductase antibody, Fragile site FRA16D Oxireductase antibody, HHCMA56 antibody, MGC55975 antibody, PRO0128 antibody, Putative oxidoreductase antibody, SCAR12 antibody, SDR41C1 antibody, Short chain dehydrogenase/reductase family 41C, member 1 antibody, WOX1 antibody, WW domain containing oxidoreductase antibody, WW domain-containing oxidoreductase antibody, WW domain-containing protein WWOX antibody, wwox antibody, WWOX_HUMAN antibody, zgc:55975 antibody

UniProt: Q9NZC7