CCDC53 antibody (AA 1-194)

Catalog No. ABIN7175683

Product Details anti-CCDC53 Antibody

Target: CCDC53 (Coiled-Coil Domain Containing 53 (CCDC53))

Binding Specificity: AA 1-194

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC53 antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human WASH complex subunit 3 protein (1-194AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CCDC53

Target: CCDC53 (Coiled-Coil Domain Containing 53 (CCDC53))

Alternative Name: WASHC3 (CCDC53 Products)

Synonyms: RGD1563761 antibody, zgc:55718 antibody, CGI-116 antibody, 2900091E11Rik antibody, 5730495F03Rik antibody, ccdc53 antibody, WASH complex subunit 3 antibody, WASH complex subunit 3 L homeolog antibody, coiled-coil domain containing 53 antibody, Coiled-coil domain-containing protein 53 antibody, Washc3 antibody, washc3 antibody, WASHC3 antibody, washc3.L antibody, Ccdc53 antibody

Background:

Background: Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093).

Aliases: WASHC3 antibody, AD-016 antibody, CCDC53 antibody, CGI-116 antibody, x0009 antibody, WASH complex subunit 3 antibody, Coiled-coil domain-containing protein 53 antibody

UniProt: Q9Y3C0