PTPLAD1 antibody (AA 1-145)

Catalog No. ABIN7175445

Product Details anti-PTPLAD1 Antibody

Target: PTPLAD1 (Protein tyrosine Phosphatase-Like A Domain Containing 1 (PTPLAD1))

Binding Specificity: AA 1-145

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPLAD1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 protein (1-145AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PTPLAD1

Target: PTPLAD1 (Protein tyrosine Phosphatase-Like A Domain Containing 1 (PTPLAD1))

Alternative Name: HACD3 (PTPLAD1 Products)

Synonyms: B-IND1 antibody, HACD3 antibody, HSPC121 antibody, 4930523M17Rik antibody, AW742319 antibody, B-ind1 antibody, Hspc121 antibody, RGD1565496 antibody, HACD antibody, 3-hydroxyacyl-CoA dehydratase 3 antibody, HACD3 antibody, Hacd3 antibody

Background:

Background: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May be involved in Rac1-signaling pathways leading to the modulation of gene expression. Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization (PubMed:25687571).

Aliases: HACD3 antibody, BIND1 antibody, PTPLAD1 antibody, Very-long-chain antibody, 3R)-3-hydroxyacyl-CoA dehydratase 3 antibody, EC 4.2.1.134 antibody, 3-hydroxyacyl-CoA dehydratase 3 antibody, HACD3 antibody, Butyrate-induced protein 1 antibody, B-ind1 antibody, hB-ind1 antibody, Protein-tyrosine phosphatase-like A domain-containing protein 1 antibody

UniProt: Q9P035