VPS39 antibody (AA 263-490)

Catalog No. ABIN7175353

Product Details anti-VPS39 Antibody

Target: VPS39 (Vacuolar Protein Sorting 39 Homolog (VPS39))

Binding Specificity: AA 263-490

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS39 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Vam6/Vps39-like protein (263-490AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for VPS39

Target: VPS39 (Vacuolar Protein Sorting 39 Homolog (VPS39))

Alternative Name: VPS39 (VPS39 Products)

Synonyms: lbk antibody, vam6 antibody, DKFZp469J2314 antibody, A230065P22Rik antibody, AW743070 antibody, Vam6 antibody, Vam6P antibody, mVam6 antibody, TLP antibody, VAM6 antibody, hVam6p antibody, VPS39, HOPS complex subunit antibody, vacuolar protein sorting 39 homolog (S. cerevisiae) antibody, vam6/Vps39-like protein antibody, vacuolar protein sorting 39 antibody, VPS39 HOPS complex subunit antibody, VPS39 antibody, vps39 antibody, LOC100196283 antibody, NAEGRDRAFT_59276 antibody, Vps39 antibody

Background:

Background: Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription. Does not affect TGF-beta-induced SMAD2 or SMAD3 phosphorylation, nor SMAD2/SMAD4 complex formation.

Aliases: A230065P22Rik antibody, AW743070 antibody, FLJ21681 antibody, FLJ46546 antibody, hVam6p antibody, KIAA0770 antibody, RP23-348L16.12 antibody, TLP antibody, TRAP1 like protein antibody, Vacuolar protein sorting 39 antibody, Vacuolar protein sorting 39 homolog antibody, VAM6 antibody, Vam6/Vps39 like antibody, Vam6/Vps39 like protein antibody, Vam6/Vps39-like protein antibody, VPS 39 antibody, Vps39 antibody, VPS39_HUMAN antibody

UniProt: Q96JC1

Pathways: SARS-CoV-2 Protein Interactome