VPS39 antibody (AA 263-490)

Catalog No. ABIN7175353

Product Details anti-VPS39 Antibody

Target: VPS39 (Vacuolar Protein Sorting 39 Homolog (VPS39))

Binding Specificity: AA 263-490

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS39 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Vam6/Vps39-like protein (263-490AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for VPS39

Target: VPS39 (Vacuolar Protein Sorting 39 Homolog (VPS39))

Alternative Name: VPS39 (VPS39 Products)

Background:

Background: Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription. Does not affect TGF-beta-induced SMAD2 or SMAD3 phosphorylation, nor SMAD2/SMAD4 complex formation.

Aliases: A230065P22Rik antibody, AW743070 antibody, FLJ21681 antibody, FLJ46546 antibody, hVam6p antibody, KIAA0770 antibody, RP23-348L16.12 antibody, TLP antibody, TRAP1 like protein antibody, Vacuolar protein sorting 39 antibody, Vacuolar protein sorting 39 homolog antibody, VAM6 antibody, Vam6/Vps39 like antibody, Vam6/Vps39 like protein antibody, Vam6/Vps39-like protein antibody, VPS 39 antibody, Vps39 antibody, VPS39_HUMAN antibody

UniProt: Q96JC1

Pathways: SARS-CoV-2 Protein Interactome