VPS52 antibody (AA 277-377)

Catalog No. ABIN7175328

Product Details anti-VPS52 Antibody

Target: VPS52 (Vacuolar Protein Sorting 52 Homolog (VPS52))

Binding Specificity: AA 277-377

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS52 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Vacuolar protein sorting-associated protein 52 homolog protein (277-377AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for VPS52

Target: VPS52 (Vacuolar Protein Sorting 52 Homolog (VPS52))

Alternative Name: VPS52 (VPS52 Products)

Synonyms: ARE1 antibody, RP5-1033B10 antibody, SAC2 antibody, SACM2L antibody, dJ1033B10.5 antibody, Are1 antibody, Sacm2l antibody, D130068D18 antibody, D430041K17Rik antibody, fb94c11 antibody, sacm2l antibody, wu:fb94c11 antibody, VPS52, GARP complex subunit antibody, VPS52 GARP complex subunit antibody, vacuolar protein sorting 52 homolog (S. cerevisiae) antibody, VPS52 antibody, Vps52 antibody, vps52 antibody

Background:

Background: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).

Aliases: VPS52 antibody, SACM2LVacuolar protein sorting-associated protein 52 homolog antibody, SAC2 suppressor of actin mutations 2-like protein antibody

UniProt: Q8N1B4