Myosin VIIA antibody (AA 838-968)

Catalog No. ABIN7174961

Product Details anti-Myosin VIIA Antibody

Target: Myosin VIIA (MYO7A)

Binding Specificity: AA 838-968

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin VIIA antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Unconventional myosin-VIIa protein (838-968AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Myosin VIIA

Target: Myosin VIIA (MYO7A)

Alternative Name: MYO7A (MYO7A Products)

Synonyms: 53D10S antibody, BG:DS00929.11 antibody, CG7595 antibody, D antibody, D2 antibody, DM7a antibody, DMyoVIIa antibody, Dm 35B antibody, DmVIIA antibody, DmVIIa antibody, Dmel\\CG7595 antibody, Dro35B antibody, ESTS:53D10S antibody, Mhc35BC antibody, MyoVIIA antibody, anon-35Bb antibody, br27 antibody, ck/MyoVIIA antibody, l(1)35Ca antibody, l(2)07130 antibody, l(2)35Ca antibody, l(2)br27 antibody, l35Ca antibody, myoVIIA antibody, stc antibody, stch antibody, myo7a antibody, MYO7A antibody, NV17859 antibody, Hdb antibody, Myo7 antibody, USH1B antibody, nmf371 antibody, polka antibody, sh-1 antibody, sh1 antibody, DFNA11 antibody, DFNB2 antibody, MYOVIIA antibody, MYU7A antibody, NSRD2 antibody, crinkled antibody, myosin VIIAa antibody, myosin VIIa antibody, myosin VIIA antibody, myosin 7A antibody, myosin-VIIa antibody, ck antibody, myo7aa antibody, LOAG_02192 antibody, MYO7A antibody, myo7a antibody, LOC663995 antibody, LOC100116446 antibody, Myo7a antibody

Background:

Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

Aliases: MYO7A antibody, USH1B antibody, Unconventional myosin-VIIa antibody

UniProt: Q13402

Pathways: Sensory Perception of Sound