MYO5B antibody (AA 1440-1690)

Catalog No. ABIN7174957

Product Details anti-MYO5B Antibody

Target: MYO5B (Myosin VB (MYO5B))

Binding Specificity: AA 1440-1690

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO5B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Unconventional myosin-Vb protein (1440-1690AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MYO5B

Target: MYO5B (Myosin VB (MYO5B))

Alternative Name: MYO5B (MYO5B Products)

Synonyms: AI661750 antibody, mKIAA1119 antibody, Myr6 antibody, myosin VB antibody, myosin Vb antibody, MYO5B antibody, Myo5b antibody

Background:

Background: May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.

Aliases: KIAA1119 antibody, Myo5b antibody, MYO5B_HUMAN antibody, Myosin Vb antibody, Unconventional myosin-Vb antibody

UniProt: Q9ULV0