MYO1E antibody (AA 62-189)

Catalog No. ABIN7174945

Product Details anti-MYO1E Antibody

Target: MYO1E (Myosin IE (MYO1E))

Binding Specificity: AA 62-189

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO1E antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Unconventional myosin-Ie protein (62-189AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MYO1E

Target: MYO1E (Myosin IE (MYO1E))

Alternative Name: MYO1E (MYO1E Products)

Synonyms: FSGS6 antibody, HuncM-IC antibody, MYO1C antibody, MYR5 antibody, Myr3 antibody, 2310020N23Rik antibody, 9130023P14Rik antibody, AA407778 antibody, myosin-1e antibody, myr 3 antibody, myo1e antibody, wu:fc15g04 antibody, wu:fe49h01 antibody, myosin IE antibody, myosin IE, a antibody, MYO1E antibody, Myo1e antibody, myo1ea antibody

Background:

Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14.

Aliases: FSGS6 antibody, HuncM-IC antibody, MYO1C antibody, Myo1e antibody, MYO1E variant protein antibody, MYO1E_HUMAN antibody, Myosin heavy chain myr 3 antibody, Myosin IC, formerly antibody, Myosin IE antibody, Myosin-Ic antibody, Myr 3 antibody, Myr3 antibody, MYR5 antibody, Unconventional myosin 1E antibody, Unconventional myosin Ie antibody, Unconventional myosin-Ie antibody

UniProt: Q12965

Pathways: Platelet-derived growth Factor Receptor Signaling