GALE antibody (AA 1-348)

Catalog No. ABIN7174611

Product Details anti-GALE Antibody

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Binding Specificity: AA 1-348

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human UDP-glucose 4-epimerase protein (1-348AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GALE

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Alternative Name: GALE (GALE Products)

Background:

Background: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.

Aliases: FLJ95174 antibody, FLJ97302 antibody, Galactose 4 epimerase UDP antibody, Galactowaldenase antibody, galE antibody, GALE_HUMAN antibody, OTTHUMP00000002991 antibody, OTTHUMP00000002994 antibody, OTTHUMP00000037931 antibody, OTTHUMP00000044857 antibody, SDR1E1 antibody, short chain dehydrogenase/reductase family 1E member 1 antibody, UDP galactose 4 epimerase antibody, UDP galactose 4' epimerase antibody, UDP glucose 4 epimerase antibody, UDP-galactose 4-epimerase antibody, UDP-glucose 4-epimerase antibody

UniProt: Q14376

Pathways: Response to Water Deprivation, Cellular Glucan Metabolic Process