UBE3C antibody (AA 310-377)

Catalog No. ABIN7174575

Product Details anti-UBE3C Antibody

Target: UBE3C (Ubiquitin Protein Ligase E3C (UBE3C))

Binding Specificity: AA 310-377

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE3C antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin-protein ligase E3C protein (310-377AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UBE3C

Target: UBE3C (Ubiquitin Protein Ligase E3C (UBE3C))

Alternative Name: UBE3C (UBE3C Products)

Synonyms: UBE3C antibody, RGD1559986 antibody, zgc:63649 antibody, AI853514 antibody, mKIAA0010 antibody, HECTH2 antibody, kiaa0010 antibody, MGC146390 antibody, ubiquitin protein ligase E3C antibody, ubiquitin protein ligase E3C S homeolog antibody, UBE3C antibody, Ube3c antibody, ube3c antibody, ube3c.S antibody

Background:

Background: E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either \'Lys-29\'- or \'Lys-48\'-linked polyubiquitin chains. Has preference for \'Lys-48\' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.

Aliases: HectH2 antibody, KIAA0010 antibody, KIAA10 antibody, Ube3c antibody, UBE3C_HUMAN antibody, Ubiquitin protein isopeptide ligase (E3) antibody, Ubiquitin protein ligase E3C antibody, Ubiquitin-protein ligase E3C antibody

UniProt: Q15386