Ube2t antibody (AA 1-197) (Biotin)

Catalog No. ABIN7174486

Product Details anti-Ube2t Antibody (Biotin)

Target: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Binding Specificity: AA 1-197

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ube2t antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin-conjugating enzyme E2 T protein (1-197AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Ube2t

Target: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Alternative Name: UBE2T (Ube2t Products)

Synonyms: PIG50 antibody, UBE2T antibody, 2700084L22Rik antibody, C80607 antibody, RGD1310816 antibody, hspc150 antibody, wu:fj86h11 antibody, zgc:153687 antibody, ubiquitin conjugating enzyme E2 T antibody, ubiquitin-conjugating enzyme E2T antibody, ubiquitin conjugating enzyme E2T S homeolog antibody, ubiquitin-conjugating enzyme E2T (putative) antibody, UBE2T antibody, Ube2t antibody, ube2t.S antibody, ube2t antibody

Background:

Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer \'Lys-11\'-, \'Lys-27\'-, \'Lys-48\'- and \'Lys-63\'-linked polyubiquitination.

Aliases: Cell proliferation inducing gene 50 protein antibody, Cell proliferation-inducing gene 50 protein antibody, HSPC150 antibody, HSPC150 protein similar to ubiquitin conjugating enzyme antibody, PIG50 antibody, Ube2t antibody, UBE2T_HUMAN antibody, Ubiquitin carrier protein T antibody, Ubiquitin conjugating enzyme antibody, ubiquitin conjugating enzyme E2 T antibody, Ubiquitin conjugating enzyme E2T antibody, Ubiquitin protein ligase T antibody, Ubiquitin-conjugating enzyme E2 T antibody, Ubiquitin-protein ligase T antibody

UniProt: Q9NPD8

Pathways: Chromatin Binding