UBASH3B antibody (AA 1-300)

Catalog No. ABIN7174417

Product Details anti-UBASH3B Antibody

Target: UBASH3B (STS1) (Cbl-Interacting Protein Sts-1 (STS1))

Binding Specificity: AA 1-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBASH3B antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ubiquitin-associated and SH3 domain-containing protein B protein (1-300AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UBASH3B

Target: UBASH3B (STS1) (Cbl-Interacting Protein Sts-1 (STS1))

Alternative Name: UBASH3B (STS1 Products)

Synonyms: STS-1 antibody, STS1 antibody, TULA-2 antibody, p70 antibody, 2810457I06Rik antibody, BB125008 antibody, RGD1310357 antibody, Sts-1 antibody, ubiquitin associated and SH3 domain containing B antibody, ubiquitin associated and SH3 domain containing, B antibody, UBASH3B antibody, Ubash3b antibody

Background:

Background: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.

Aliases: Cbl interacting protein p70 antibody, Cbl interacting protein Sts 1 antibody, Cbl interacting protein Sts1 antibody, Cbl-interacting protein p70 antibody, KIAA1959 antibody, MGC15437 antibody, Nm23 phosphorylated unknown substrate antibody, p70 antibody, SH3 domain containing 70 kDa protein antibody, Sts 1 antibody, STS-1 antibody, STS1 antibody, Suppressor of T cell receptor signaling 1 antibody, Suppressor of T-cell receptor signaling 1 antibody, T-cell ubiquitin ligand 2 antibody, TULA-2 antibody, Tyrosine-protein phosphatase STS1/TULA2 antibody, Ubash3b antibody, Ubiquitin associated and SH3 domain containing B antibody, Ubiquitin-associated and SH3 domain-containing protein B antibody, UBS3B_HUMAN antibody

UniProt: Q8TF42