ZRANB1 antibody (AA 111-397) (Biotin)

Catalog No. ABIN7174402

Product Details anti-ZRANB1 Antibody (Biotin)

Target: ZRANB1 (Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1))

Binding Specificity: AA 111-397

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZRANB1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin thioesterase ZRANB1 protein (111-397AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ZRANB1

Target: ZRANB1 (Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1))

Alternative Name: ZRANB1 (ZRANB1 Products)

Synonyms: TRABID antibody, 9330160G10Rik antibody, D7Wsu87e antibody, Gm1956 antibody, Trabid antibody, trabid antibody, zranb1 antibody, zgc:154177 antibody, zinc finger RANBP2-type containing 1 antibody, zinc finger, RAN-binding domain containing 1 antibody, zinc finger RANBP2-type containing 1 L homeolog antibody, zinc finger, RAN-binding domain containing 1b antibody, ZRANB1 antibody, Zranb1 antibody, zranb1.L antibody, zranb1b antibody, zranb1 antibody

Background:

Background: Specifically hydrolyzes \'Lys-29\'-linked and \'Lys-33\'-linked diubiquitin. Also cleaves \'Lys-63\'-linked chains, but with 40-fold less efficiency compared to \'Lys-29\'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.

Aliases: DKFZp762P2216 antibody, hTrabid antibody, Trabid antibody, TRAF-binding protein domain antibody, Ubiquitin thioesterase ZRANB1 antibody, Zinc finger Ran-binding domain-containing protein 1 antibody, ZRAN1_HUMAN antibody, ZRANB1 antibody

UniProt: Q9UGI0