YOD1 antibody (AA 1-44) (Biotin)

Catalog No. ABIN7174390

Product Details anti-YOD1 Antibody (Biotin)

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Binding Specificity: AA 1-44

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YOD1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin thioesterase OTU1 protein (1-44AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for YOD1

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Alternative Name: YOD1 (YOD1 Products)

Synonyms: DUBA8 antibody, OTUD2 antibody, PRO0907 antibody, hshin7 antibody, wu:fe01a10 antibody, zgc:112182 antibody, 9930028C20Rik antibody, Hshin7 antibody, YOD1 deubiquitinase antibody, YOD1 deubiquitinase L homeolog antibody, YOD1 antibody, Yod1 antibody, yod1.L antibody, yod1 antibody

Background:

Background: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP\'s axial channel. Mediates deubiquitination of \'Lys-27\'-, \'Lys-29\'- and \'Lys-33\'-linked polyubiquitin chains. Also able to hydrolyze \'Lys-11\'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin.

Aliases: DUBA-8 antibody, DUBA8 antibody, HIN-7 antibody, HIV-1-induced protease 7 antibody, HsHIN7 antibody, OTU domain containing 2 antibody, OTU domain-containing protein 2 antibody, OTU1_HUMAN antibody, OTUD2 antibody, PRO0907 antibody, RP11-164O23.1 antibody, Ubiquitin thioesterase OTU1 antibody, yod1 antibody, YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae) antibody, YOD1 OTU deubiquinating enzyme 1 homolog (yeast) antibody, YOD1 OTU deubiquinating enzyme 1, S. cerevisiae, homolog of antibody

UniProt: Q5VVQ6

Pathways: ER-Nucleus Signaling