USP6 antibody (C-Term) (Biotin)

Catalog No. ABIN7174353

Product Details anti-USP6 Antibody (Biotin)

Target: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Binding Specificity: AA 1122-1359, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP6 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin carboxyl-terminal hydrolase 6 protein (1122-1359AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for USP6

Target: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Alternative Name: USP6 (USP6 Products)

Synonyms: HRP1 antibody, TRE2 antibody, TRE17 antibody, Tre-2 antibody, USP6-short antibody, ubiquitin specific peptidase 6 antibody, ubiquitin carboxyl-terminal hydrolase 6 antibody, Ubiquitin carboxyl-terminal hydrolase 6, putative antibody, USP6 antibody, CNG04540 antibody, ANI_1_2152104 antibody, AOR_1_208094 antibody, MCYG_00569 antibody, CC1G_15273 antibody, MGYG_01395 antibody, CGB_G0160W antibody, LOC100282385 antibody

Background:

Background: Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Aliases: Deubiquitinating enzyme 6 antibody, HRP1 antibody, Proto-oncogene TRE-2 antibody, TRE17 antibody, TRE2 antibody, Ubiquitin carboxyl-terminal hydrolase 6 antibody, Ubiquitin specific protease 6 antibody, Ubiquitin thiolesterase 6 antibody, Ubiquitin-specific-processing protease 6 antibody, UBP6_HUMAN antibody, USP6 antibody

UniProt: P35125