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USP5 antibody (C-Term) (Biotin)

USP5 Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7174349
  • Target See all USP5 Antibodies
    USP5 (Ubiquitin Specific Peptidase 5 (USP5))
    Binding Specificity
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-500, C-Term
    Reactivity
    • 39
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 31
    • 9
    Rabbit
    Clonality
    • 32
    • 8
    Polyclonal
    Conjugate
    • 26
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP5 antibody is conjugated to Biotin
    Application
    • 27
    • 16
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 5 protein (201-500AA)
    Isotype
    IgG
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    USP5 (Ubiquitin Specific Peptidase 5 (USP5))
    Alternative Name
    USP5 (USP5 Products)
    Synonyms
    ISOT antibody, AA407472 antibody, ISOT-1 antibody, Ucht antibody, ubiquitin specific peptidase 5 antibody, ubiquitin carboxyl-terminal hydrolase 5 antibody, ubiquitin carboxyl-terminal hydrolase 5, putative antibody, ubiquitin specific protease 5 antibody, ubiquitin specific peptidase 5 (isopeptidase T) antibody, USP5 antibody, CNH02890 antibody, EHI_049940 antibody, CC1G_12961 antibody, MCYG_01862 antibody, CGB_L3600C antibody, PY00546 antibody, Usp5 antibody
    Background

    Background: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored \'Lys-48\'-linked polyubiquitin disassembly. Binds linear and \'Lys-63\'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

    Aliases: Deubiquitinating enzyme 5 antibody, Isopeptidase T antibody, ISOT 1 antibody, ISOT antibody, Ubiquitin carboxyl-terminal hydrolase 5 antibody, Ubiquitin isopeptidase T antibody, Ubiquitin specific peptidase 5 (isopeptidase T) antibody, Ubiquitin specific peptidase 5 antibody, Ubiquitin specific processing protease 5 antibody, Ubiquitin specific protease 5 (isopeptidase T) antibody, Ubiquitin specific protease 5 (ubiquitin isopeptidase T) antibody, Ubiquitin thioesterase 5 antibody, Ubiquitin thiolesterase 5 antibody, Ubiquitin-specific-processing protease 5 antibody, UBP5_HUMAN antibody, Usp5 antibody

    UniProt
    P45974
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