USP47 antibody (AA 1-157) (Biotin)

Catalog No. ABIN7174341

Product Details anti-USP47 Antibody (Biotin)

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Binding Specificity: AA 1-157

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP47 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin carboxyl-terminal hydrolase 47 protein (1-157AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for USP47

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Alternative Name: USP47 (USP47 Products)

Synonyms: USP47 antibody, zgc:165650 antibody, TRFP antibody, 4930502N04Rik antibody, A630020C16Rik antibody, ubiquitin specific peptidase 47 antibody, ubiquitin carboxyl-terminal hydrolase 47 antibody, ubiquitin specific peptidase 47 S homeolog antibody, Usp47 antibody, USP47 antibody, usp47 antibody, LOC100639726 antibody, usp47.S antibody

Background:

Background: Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level.

Aliases: Deubiquitinating enzyme 47 antibody, TFRP antibody, Trf TATA binding protein related factor proximal homolog antibody, Trf TATA binding protein related factor proximal homolog Drosophila antibody, Ubiquitin carboxyl-terminal hydrolase 47 antibody, Ubiquitin specific peptidase 47 antibody, Ubiquitin specific processing protease 47 antibody, Ubiquitin specific protease 47 antibody, Ubiquitin thioesterase 47 antibody, Ubiquitin thiolesterase 47 antibody, Ubiquitin-specific-processing protease 47 antibody, UBP47_HUMAN antibody, USP47 antibody

UniProt: Q96K76

Pathways: Negative Regulation of intrinsic apoptotic Signaling