C10orf2 antibody (AA 559-684)

Catalog No. ABIN7173941

Product Details anti-C10orf2 Antibody

Target: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Binding Specificity: AA 559-684

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C10orf2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Twinkle protein, mitochondrial protein (559-684AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for C10orf2

Target: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Alternative Name: TWNK (C10ORF2 Products)

Synonyms: ATXN8 antibody, IOSCA antibody, MTDPS7 antibody, PEO antibody, PEO1 antibody, PEOA3 antibody, SANDO antibody, SCA8 antibody, TWINL antibody, C6H10orf2 antibody, D19Ertd626e antibody, Twinl antibody, twinkle mtDNA helicase L homeolog antibody, twinkle mtDNA helicase antibody, twnk.L antibody, TWNK antibody, Twnk antibody

Background:

Background: Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function inferred to be critical for lifetime maintenance of mtDNA integrity. In vitro, forms in combination with POLG, a processive replication machinery, which can use double-stranded DNA (dsDNA) as template to synthesize single-stranded DNA (ssDNA) molecules. May be a key regulator of mtDNA copy number in mammals.

Aliases: Ataxin 8 antibody, Ataxin8 antibody, ATXN 8 antibody, ATXN8 antibody, C10 orf2 antibody, C10orf 2 antibody, C10orf2 antibody, Chromosome 10 open reading frame 2 antibody, IOSCA antibody, mitochondrial antibody, MTDPS7 antibody, PEO 1 antibody, PEO antibody, PEO1 antibody, PEO1_HUMAN antibody, PEOA3 antibody, Progressive external ophthalmoplegia 1 protein antibody, SANDO antibody, SCA 8 antibody, SCA8 antibody, T7 gp4 like protein with intramitochondrial nucleoid localization antibody, T7 gp4-like protein with intramitochondrial nucleoid localization antibody, T7 helicase-related protein with intramitochondrial nucleoid localization antibody, T7 like mitochondrial DNA helicase antibody, T7-like mitochondrial DNA helicase antibody, Twinkle protein antibody, Twinkle protein, mitochondrial antibody, TWINL antibody

UniProt: Q96RR1