TDRD1 antibody (AA 12-314)

Catalog No. ABIN7173760

Product Details anti-TDRD1 Antibody

Target: TDRD1 (Tudor Domain Containing 1 (TDRD1))

Binding Specificity: AA 12-314

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDRD1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Tudor domain-containing protein 1 protein (12-314AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TDRD1

Target: TDRD1 (Tudor Domain Containing 1 (TDRD1))

Alternative Name: TDRD1 (TDRD1 Products)

Synonyms: CT41.1 antibody, MTR-1 antibody, im:7155161 antibody, tudor domain containing 1 antibody, TDRD1 antibody, Tdrd1 antibody, tdrd1 antibody

Background:

Background: Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins (By similarity).

Aliases: Cancer/testis antigen 41.1 antibody, CT41.1 antibody, FLJ21082 antibody, MTR 1 antibody, TDRD 1 antibody, tdrd1 antibody, TDRD1_HUMAN antibody, Tudor domain containing 1 antibody, Tudor domain containing protein 1 antibody, Tudor domain-containing protein 1 antibody

UniProt: Q9BXT4

Pathways: Ribonucleoprotein Complex Subunit Organization