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TBCD antibody (AA 2-96) (HRP)

TBCD Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7173753
  • Target See all TBCD Antibodies
    TBCD (Tubulin Folding Cofactor D (TBCD))
    Binding Specificity
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 2-96
    Reactivity
    • 10
    • 2
    • 1
    Human
    Host
    • 9
    • 2
    Rabbit
    Clonality
    • 11
    Polyclonal
    Conjugate
    • 9
    • 1
    • 1
    This TBCD antibody is conjugated to HRP
    Application
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Tubulin-specific chaperone D protein (2-96AA)
    Isotype
    IgG
    Top Product
    Discover our top product TBCD Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TBCD (Tubulin Folding Cofactor D (TBCD))
    Alternative Name
    TBCD (TBCD Products)
    Synonyms
    SSD-1 antibody, tfcD antibody, 2310057L06Rik antibody, A030005L14Rik antibody, mKIAA0988 antibody, tubulin folding cofactor D antibody, tubulin-specific chaperone d antibody, TBCD antibody, Tbcd antibody
    Background

    Background: Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane (PubMed:10722852, PubMed:10831612, PubMed:11847227, PubMed:20740604, PubMed:27666370, PubMed:28158450). Required for correct assembly and maintenance of the mitotic spindle, and proper progression of mitosis (PubMed:27666370). Involved in neuron morphogenesis (PubMed:27666374).

    Aliases: Beta tubulin cofactor D antibody, Beta-tubulin cofactor D antibody, KIAA0988 antibody, SSD 1 antibody, SSD-1 antibody, SSD1 antibody, tbcd antibody, TBCD_HUMAN antibody, tfcD antibody, Tubulin folding cofactor D antibody, Tubulin specific chaperone D antibody, Tubulin-folding cofactor D antibody, Tubulin-specific chaperone D antibody

    UniProt
    Q9BTW9
    Pathways
    Cell-Cell Junction Organization
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