TULP3 antibody (AA 1-260) (Biotin)

Catalog No. ABIN7173640

Product Details anti-TULP3 Antibody (Biotin)

Target: TULP3 (Tubby Like Protein 3 (TULP3))

Binding Specificity: AA 1-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TULP3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Tubby-related protein 3 protein (1-260AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TULP3

Target: TULP3 (Tubby Like Protein 3 (TULP3))

Alternative Name: TULP3 (TULP3 Products)

Synonyms: tubl3 antibody, DKFZp469I1734 antibody, TUBL3 antibody, 2310022L06Rik antibody, AI316887 antibody, tubby like protein 3 antibody, tubby-like protein 3 antibody, TULP3 antibody, tulp3 antibody, Tulp3 antibody

Background:

Background: Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.

Aliases: MGC45295 antibody, Tubby like protein 3 antibody, Tubby related protein 3 antibody, Tubby-like protein 3 antibody, Tubby-related protein 3 antibody, TUBL 3 antibody, TUBL3 antibody, TULP 3 antibody, TULP3 antibody, TULP3_HUMAN antibody

UniProt: O75386

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation