C2orf60 antibody (AA 1-152)

Catalog No. ABIN7173520

Product Details anti-C2orf60 Antibody

Target: C2orf60 (Chromosome 2 Open Reading Frame 60 (C2orf60))

Binding Specificity: AA 1-152

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C2orf60 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human tRNA wybutosine-synthesizing protein 5 protein (1-152AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for C2orf60

Target: C2orf60 (Chromosome 2 Open Reading Frame 60 (C2orf60))

Alternative Name: TYW5 (C2orf60 Products)

Synonyms: JMJD5 antibody, C2orf60 antibody, hTYW5 antibody, RGD1311269 antibody, C7H2orf60 antibody, 1110034B05Rik antibody, tRNA-yW synthesizing protein 5 antibody, TYW5 antibody, Tyw5 antibody

Background:

Background: tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3\\\'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes.

Aliases: TYW5 antibody, C2orf60 antibody, tRNA wybutosine-synthesizing protein 5 antibody, hTYW5 antibody, EC 1.14.11.42 antibody, tRNA(Phe antibody, 7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase antibody

UniProt: A2RUC4

Pathways: Ribonucleoside Biosynthetic Process