NSUN2 antibody (AA 432-509)

Catalog No. ABIN7173496

Product Details anti-NSUN2 Antibody

Target: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Binding Specificity: AA 432-509

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSUN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human tRNA (cytosine(34)-C(5))-methyltransferase protein (432-509AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NSUN2

Target: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Alternative Name: NSUN2 (NSUN2 Products)

Synonyms: D13Wsu123e antibody, Misu antibody, MISU antibody, MRT5 antibody, SAKI antibody, TRM4 antibody, RGD1311954 antibody, NOL1/NOP2/Sun domain family member 2 antibody, NOP2/Sun RNA methyltransferase family member 2 antibody, NOP2/Sun RNA methyltransferase family, member 2 antibody, NOP2/Sun RNA methyltransferase family member 2 S homeolog antibody, Nsun2 antibody, NSUN2 antibody, nsun2.S antibody

Background:

Background: RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

Aliases: 5 methycytoisine methyltransferase antibody, D13Wsu123e antibody, FLJ20303 antibody, hTrm4 antibody, MISU antibody, Myc induced SUN domain containing protein antibody, NOL1/NOP2/Sun domain family 2 antibody, NOL1/NOP2/Sun domain family 2 protein antibody, NOL1/NOP2/Sun domain family member 2 antibody, NSUN 2 antibody, NSUN2 antibody, NSUN2_HUMAN antibody, SAKI antibody, Substrate of AIM1/Aurora kinase B antibody, TRM4 antibody, tRNA (cytosine 5 ) methyltransferase antibody, tRNA (cytosine 5 ) methyltransferase NSUN2 antibody, tRNA (cytosine(34)-C(5))-methyltransferase antibody, tRNA (cytosine-5-)-methyltransferase antibody, tRNA methyltransferase 4 homolo antibody, tRNA methyltransferase 4 homolog antibody

UniProt: Q08J23