TNRC6C antibody (AA 157-421) (Biotin)

Catalog No. ABIN7173408

Product Details anti-TNRC6C Antibody (Biotin)

Target: TNRC6C (Trinucleotide Repeat Containing 6C (TNRC6C))

Binding Specificity: AA 157-421

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNRC6C antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Trinucleotide repeat-containing gene 6C protein (157-421AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TNRC6C

Target: TNRC6C (Trinucleotide Repeat Containing 6C (TNRC6C))

Alternative Name: TNRC6C (TNRC6C Products)

Synonyms: 9930033H14Rik antibody, mKIAA1582 antibody, trinucleotide repeat containing 6C antibody, TNRC6C antibody, Tnrc6c antibody

Background:

Background: Plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs). Required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.

Aliases: KIAA1582 antibody, TNR6C_HUMAN antibody, TNRC 6C antibody, Tnrc6c antibody, Trinucleotide repeat containing 6C antibody, Trinucleotide repeat containing gene 6C protein antibody, Trinucleotide repeat-containing gene 6C protein antibody

UniProt: Q9HCJ0

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway