TRAPPC10 antibody (AA 1-55)

Catalog No. ABIN7173019

Product Details anti-TRAPPC10 Antibody

Target: TRAPPC10 (TMEM1) (Transmembrane Protein 1 (TMEM1))

Binding Specificity: AA 1-55

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAPPC10 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Transmembrane protein 100 protein (1-55AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TRAPPC10

Target: TRAPPC10 (TMEM1) (Transmembrane Protein 1 (TMEM1))

Alternative Name: TMEM1 (TMEM1 Products)

Synonyms: EHOC-1 antibody, EHOC1 antibody, GT334 antibody, TMEM1 antibody, TRS130 antibody, TRS30 antibody, B230307C21Rik antibody, Gm870 antibody, Tmem1 antibody, trafficking protein particle complex 10 antibody, TRAPPC10 antibody, Trappc10 antibody

Background:

Background: Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.

Aliases: TMEM100 antibody, Transmembrane protein 100 antibody

UniProt: Q9NV29