TMPRSS11D antibody (AA 201-418)

Catalog No. ABIN7173007

Product Details anti-TMPRSS11D Antibody

Target: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Binding Specificity: AA 201-418

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS11D antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Transmembrane protease serine 11D protein (201-418AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TMPRSS11D

Target: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Alternative Name: TMPRSS11D (TMPRSS11D Products)

Background:

Background: May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Proteolytically cleaves and activates the human coronavirus 229E (HCoV-229E) spike glycoprotein which facilitate virus-cell membrane fusions, spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence.

Aliases: Airway trypsin like protease antibody, Airway trypsin-like protease antibody, HAT antibody, MGC150587 antibody, MGC150588 antibody, TM11D_HUMAN antibody, TMPRSS11D antibody, Transmembrane protease serine 11D antibody, Transmembrane protease serine 11D catalytic chain antibody, Transmembrane protease serine 11D precursor antibody

UniProt: O60235

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process