SOX3 antibody (AA 4-118) (HRP)

Catalog No. ABIN7172626

Product Details anti-SOX3 Antibody (HRP)

Target: SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))

Binding Specificity: AA 4-118

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX3 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Transcription factor SOX-3 protein (4-118AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SOX3

Target: SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))

Alternative Name: SOX3 (SOX3 Products)

Background:

Background: Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity).

Aliases: GHDX antibody, MRGH antibody, PHP antibody, PHPX antibody, sox3 antibody, SOX3_HUMAN antibody, SOXB antibody, SRY (sex determining region Y)-box 3 antibody, SRY Box 3 antibody, SRY-related HMG-box gene 3 antibody, Transcription factor Sox-3 antibody

UniProt: P41225