SOX17 antibody (AA 177-414)

Catalog No. ABIN7172611

Product Details anti-SOX17 Antibody

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Binding Specificity: AA 177-414

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX17 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Transcription factor SOX-17 protein (177-414AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SOX17

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Alternative Name: SOX17 (SOX17 Products)

Synonyms: VUR3 antibody, SOX17 antibody, Sox17alpha antibody, Xsox17 antibody, Xsox17-alpha antibody, Xsox17alpha antibody, sox17-alpha antibody, tSox17alpha antibody, xSox17alpha1 antibody, xSox17alpha2 antibody, xsox17a antibody, sox17 antibody, sox7/17 antibody, Sox antibody, SRY-box 17 antibody, SRY (sex determining region Y)-box 17 antibody, SRY box 17 antibody, SRY-box 17 alpha antibody, sox7/17 protein antibody, SOX17 antibody, sox17 antibody, Sox17 antibody, sox17a antibody, sox7/17 antibody

Background:

Background: Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5\'-AACAAT-\'3 or 5\'-AACAAAG-3\'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity).

Aliases: FLJ22252 antibody, SOX17 antibody, SOX17_HUMAN antibody, SRY (sex determining region Y) box 17 antibody, SRY box 17 antibody, SRY related HMG box transcription factor SOX17 antibody, Transcription factor SOX-17 antibody, Transcription factor SOX17 antibody, VUR3 antibody

UniProt: Q9H6I2