TFE3 antibody (AA 1-110) (Biotin)

Catalog No. ABIN7172531

Product Details anti-TFE3 Antibody (Biotin)

Target: TFE3 (Transcription Factor E3 (TFE3))

Binding Specificity: AA 1-110

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFE3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Transcription factor E3 protein (1-110AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TFE3

Target: TFE3 (Transcription Factor E3 (TFE3))

Alternative Name: TFE3 (TFE3 Products)

Synonyms: RCCP2 antibody, RCCX1 antibody, TFEA antibody, bHLHe33 antibody, F830016E06Rik antibody, Tcfe3 antibody, Tfe-3 antibody, RGD1559642 antibody, cb873 antibody, zgc:109815 antibody, transcription factor binding to IGHM enhancer 3 antibody, transcription factor E3 antibody, transcription factor binding to IGHM enhancer 3 S homeolog antibody, transcription factor binding to IGHM enhancer 3a antibody, TFE3 antibody, Tfe3 antibody, tfe3.S antibody, tfe3a antibody

Background:

Background: Transcription factor that specifically recognizes and binds E-box sequences (5\'-CANNTG-3\'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

Aliases: bHLH e33 antibody, bHLHe33 antibody, Class E basic helix-loop-helix protein 33 antibody, RCCP 2 antibody, RCCP2 antibody, RCCX1 antibody, Renal cell carcinoma, papillary antibody, Tcfe 3 antibody, Tcfe3 antibody, TFE 3 antibody, Tfe3 antibody, TFE3_HUMAN antibody, TFEA antibody, Transcription factor binding to IGHM enhancer 3 antibody, Transcription factor E family, member A antibody, Transcription factor E3 antibody, Transcription factor for IgH enhancer antibody, Transcription factor for immunoglobulin heavy chain enhancer 3 antibody

UniProt: P19532