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E2F6 antibody (AA 1-281)

E2F6 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7172529
  • Target See all E2F6 Antibodies
    E2F6 (E2F Transcription Factor 6 (E2F6))
    Binding Specificity
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-281
    Reactivity
    • 38
    • 23
    • 18
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Human
    Host
    • 30
    • 7
    • 1
    Rabbit
    Clonality
    • 31
    • 7
    Polyclonal
    Conjugate
    • 31
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This E2F6 antibody is un-conjugated
    Application
    • 29
    • 11
    • 10
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Transcription factor E2F6 protein (1-281AA)
    Isotype
    IgG
    Top Product
    Discover our top product E2F6 Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    E2F6 (E2F Transcription Factor 6 (E2F6))
    Alternative Name
    E2F6 (E2F6 Products)
    Synonyms
    E2F-6 antibody, AI462434 antibody, E2F6b antibody, EMA antibody, E2F transcription factor 6 antibody, E2F6 antibody, E2f6 antibody
    Background

    Background: Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5\\\'-TTTC[CG]CGC-3\\\'. Has a preference for the 5\\\'-TTTCCCGC-3\\\' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.

    Aliases: E2F 6 antibody, E2F binding site modulating activity protein antibody, E2F transcription factor 6 antibody, E2F transcription factor 6 isoform 1 antibody, E2F-6 antibody, E2F6 antibody, E2F6_HUMAN antibody, EMA antibody, MGC111545 antibody, Transcription factor E2F6 antibody

    UniProt
    O75461
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