ENY2 antibody (AA 1-101) (HRP)

Catalog No. ABIN7172410

Product Details anti-ENY2 Antibody (HRP)

Target: ENY2 (Enhancer of Yellow 2 Homolog (ENY2))

Binding Specificity: AA 1-101

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENY2 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Transcription and mRNA export factor ENY2 protein (1-101AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ENY2

Target: ENY2 (Enhancer of Yellow 2 Homolog (ENY2))

Alternative Name: ENY2 (ENY2 Products)

Synonyms: e(y)2 antibody, 1810057B09Rik antibody, 6720481I12 antibody, DC6 antibody, Ey2 antibody, zgc:92656 antibody, enhancer of yellow 2 homolog L homeolog antibody, ENY2, transcription and export complex 2 subunit antibody, enhancer of yellow 2 homolog (Drosophila) antibody, eny2.L antibody, ENY2 antibody, Eny2 antibody, eny2 antibody

Background:

Background: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.

Aliases: 1810057B09Rik antibody, 6720481I12 antibody, DC6 antibody, e(y)2 antibody, Enhancer of yellow 2 transcription factor homolog antibody, eny2 antibody, ENY2_HUMAN antibody, Ey2 antibody

UniProt: Q9NPA8