TIFA antibody (AA 1-184) (Biotin)

Catalog No. ABIN7172333

Product Details anti-TIFA Antibody (Biotin)

Target: TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))

Binding Specificity: AA 1-184

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIFA antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human TRAF-interacting protein with FHA domain-containing protein A protein (1-184AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TIFA

Target: TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))

Alternative Name: TIFA (TIFA Products)

Synonyms: TIFA antibody, xtifa antibody, T2BP antibody, T6BP antibody, TIFAA antibody, T2bp antibody, Ab2-389 antibody, TRAF interacting protein with forkhead associated domain antibody, TRAF-interacting protein with forkhead-associated domain antibody, TRAF-interacting protein with forkhead-associated domain S homeolog antibody, TIFA antibody, tifa antibody, Tifa antibody, tifa.S antibody

Background:

Background: Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.

Aliases: Putative MAPK activating protein PM14 antibody, Putative MAPK-activating protein PM14 antibody, Putative NF kappa B activating protein 20 antibody, Putative NF-kappa-B-activating protein 20 antibody, T2BP antibody, TIFA antibody, TIFA_HUMAN antibody, TRAF interacting protein with FHA domain containing protein A antibody, TRAF-interacting protein with FHA domain-containing protein A antibody, TRAF2 binding protein antibody, TRAF2-binding protein antibody

UniProt: Q96CG3