TANK antibody (AA 4-98)

Catalog No. ABIN7172328

Product Details anti-TANK Antibody

Target: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Binding Specificity: AA 4-98

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TANK antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human TRAF family member-associated NF-kappa-B activator protein (4-98AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TANK

Target: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Alternative Name: TANK (TANK Products)

Synonyms: I-TRAF antibody, ITRAF antibody, TRAF2 antibody, C86182 antibody, E430026L09Rik antibody, zgc:153048 antibody, i-traf antibody, tank antibody, traf2 antibody, TRAF family member associated NFKB activator antibody, TRAF family member-associated Nf-kappa B activator antibody, TRAF family member-associated NFKB activator antibody, TRAF family member associated NFKB activator L homeolog antibody, TANK antibody, Tank antibody, tank antibody, tank.L antibody

Background:

Background: Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Acts as a regulator of TRAF function by maintaining them in a latent state. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2.

Aliases: I TRAF antibody, I-TRAF antibody, ITRAF antibody, Tank antibody, TANK_HUMAN antibody, TRAF family member associated NF KAPPA B activator antibody, TRAF family member associated NFKB activator antibody, TRAF family member-associated NF-kappa-B activator antibody, TRAF interacting protein antibody, TRAF interacting protein TANK isoform a antibody, TRAF interacting protein TANK isoform b antibody, TRAF-interacting protein antibody, TRAF2 antibody

UniProt: Q92844

Pathways: p53 Signaling, TLR Signaling, Activation of Innate immune Response