TLR1 antibody (AA 25-580)

Catalog No. ABIN7172261

Product Details anti-TLR1 Antibody

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Binding Specificity: AA 25-580

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Toll-like receptor 1 protein (25-580AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TLR1

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Alternative Name: TLR1 (TLR1 Products)

Synonyms: CD281 antibody, TIL antibody, TIL. LPRS5 antibody, rsc786 antibody, toll like receptor 1 antibody, toll-like receptor 1 antibody, TLR1 antibody, Tlr1 antibody

Background:

Background: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Aliases: CD281 antibody, CD281 antigen antibody, KIAA0012 antibody, LPRS5 antibody, rsc786 antibody, TIL antibody, TIL. LPRS5 antibody, Tlr1 antibody, TLR1_HUMAN antibody, Toll (Drosophila) homolog antibody, Toll like receptor 1 antibody, Toll-like receptor 1 antibody, Toll/interleukin-1 receptor-like protein antibody

UniProt: Q15399

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades