TXNRD1 antibody (AA 1-497)

Catalog No. ABIN7172018

Product Details anti-TXNRD1 Antibody

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Binding Specificity: AA 1-497

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNRD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Thioredoxin reductase 1, cytoplasmic protein (1-497AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TXNRD1

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Alternative Name: TXNRD1 (TXNRD1 Products)

Synonyms: TrxR1 antibody, cb682 antibody, fb83a08 antibody, wu:fb83a08 antibody, GB14972 antibody, MGC85342 antibody, NADPH-dependent thioredoxin reductase C antibody, T32G6.20 antibody, T32G6_20 antibody, GRIM-12 antibody, TR antibody, TR1 antibody, TRXR1 antibody, TXNR antibody, Tr antibody, thioredoxin reductase 1 antibody, thioredoxin reductase 1 L homeolog antibody, NADPH-dependent thioredoxin reductase C antibody, ThioRedoXin Reductase antibody, TXNRD1 antibody, txnrd1 antibody, Trxr-1 antibody, txnrd1.L antibody, NTRC antibody, trxr-1 antibody, Txnrd1 antibody

Background:

Background: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

Aliases: cytoplasmic antibody, Gene associated with retinoic and IFN-induced mortality 12 protein antibody, Gene associated with retinoic and interferon-induced mortality 12 protein antibody, Gene associated with retinoid IFN induced mortality 12 protein antibody, GRIM 12 antibody, GRIM-12 antibody, GRIM12 antibody, KDRF antibody, KM 102 derived reductase like factor antibody, KM-102-derived reductase-like factor antibody, MGC9145 antibody, Oxidoreductase antibody, Thioredoxin reductase 1 antibody, Thioredoxin reductase 1 cytoplasmic antibody, Thioredoxin reductase GRIM 12 antibody, Thioredoxin reductase TR1 antibody, TR 1 antibody, TR antibody, TR1 antibody, TRXR 1 antibody, TRXR1 antibody, TRXR1_HUMAN antibody, TXNR antibody, TXNRD 1 antibody, Txnrd1 antibody

UniProt: Q16881

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis