TXN antibody (AA 2-105)

Catalog No. ABIN7172014

Product Details anti-TXN Antibody

Target: TXN (Thioredoxin (TXN))

Binding Specificity: AA 2-105

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Thioredoxin protein (2-105AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TXN

Target: TXN (Thioredoxin (TXN))

Alternative Name: TXN (TXN Products)

Synonyms: TRDX antibody, TRX antibody, TRX1 antibody, ADF antibody, AW550880 antibody, Trx1 antibody, Txn antibody, trx antibody, TXN antibody, SCM1.18 antibody, trxA3 antibody, thioredoxin antibody, TR-1 antibody, Trx-1 antibody, thioredoxin antibody, thioredoxin 1 antibody, thioredoxin L homeolog antibody, similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544) antibody, thioredoxin pseudogene antibody, cytosolic thioredoxin Trx1 antibody, TXN antibody, Txn1 antibody, txn.L antibody, txn antibody, trx antibody, SCO0885 antibody, PHG25ORF099c antibody, LOC100349046 antibody, Txn antibody, trx1 antibody

Background:

Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.

Aliases: ADF antibody, ATL derived factor antibody, ATL-derived factor antibody, DKFZp686B1993 antibody, MGC61975 antibody, SASP antibody, Surface associated sulphydryl protein antibody, Surface-associated sulphydryl protein antibody, testicular tissue protein Li 199 antibody, THIO_HUMAN antibody, Thioredoxin antibody, thioredoxin delta 3 antibody, TRDX antibody, TRX 1 antibody, Trx antibody, TRX1 antibody, TXN antibody, TXN delta 3 antibody, TXN protein antibody, zgc:92903 antibody

UniProt: P10599

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis