Tenascin N antibody (AA 441-556)

Catalog No. ABIN7171746

Product Details anti-Tenascin N Antibody

Target: Tenascin N (TNN)

Binding Specificity: AA 441-556

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tenascin N antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Tenascin-N protein (441-556AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Tenascin N

Target: Tenascin N (TNN)

Alternative Name: TNN (TNN Products)

Synonyms: TNW antibody, tenascin-N antibody, TNN antibody, TN-W antibody, Tnw antibody, tenascin-W antibody, tenascin N antibody, Tnn antibody, TNN antibody

Background:

Background: Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (By similarity) (PubMed:17909022). Involved in neurite outgrowth and cell migration in hippocampal explants (By similarity). During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling (By similarity). In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327). Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells (PubMed:17909022).

Aliases: TNN antibody, TNW antibody, Tenascin-N antibody, TN-N antibody, Tenascin-W antibody, TN-W antibody

UniProt: Q9UQP3

Pathways: ACE Inhibitor Pathway